| Place | ID | School/Affiliation | Mark | Runners |
| 1 | A | William Penn Charter (Philadelphia, PA) | 3:59.49 | Khaaleedah Smith, Saudiah Lawrence, Marquessa Gray, Elyse Wilkinson |
| 2 | H | Notre Dame Academy (Villanova, PA) | 4:01.38 | Maura McKendrick, Cassie Cummings, Dana Matteo, Ayanna Fields |
| 3 | O | Potomac School (McLean, VA) | 4:06.40 | Campbell Micar, Natalie Heintz, Katie Chockley, Trish Brandt |
| 4 | R | Connelly (Potomac, MD) | 4:06.43 | Vicky Arthur, Rachel Karanian, Alexa Yaush, Elizabeth Warren |
| 5 | F | Lawrenceville School (Lawrenceville, NJ) | 4:08.73 | Perri Smith, Kara Dreher, Jillian Ojeda, Maddie Smit |
| 6 | G | Germantown Academy (Fort Washington, PA) | 4:10.40 | Tiana North, Molly Shapiro, J. Leah Ray, Jennifer Hoy |
| 7 | N | Georgetown Day School (Washington, DC) | 4:11.13 | Adjua Pryor, Jesse Greenblatt, Elizabeth Evans, Dominique Campbell |
| 8 | B | Sidwell Friends (Washington, DC) | 4:12.66 | Lauren Lewis, Jordan Verrilli, Brooke Baldinger, Melina Greene |
| 9 | J | Peddie School (Hightstown, NJ) | 4:12.73 | Portia Jones, Raquel Koulesser, Alex Von Arx, Sarah Newbury |
| 10 | C | Friends' Central (Wynnewood, PA) | 4:13.00 | Megan Wilson, Natalie Willis, Sammie Greenberg, Tracey Weldon |
| 11 | D | Mercersburg Academy (Mercersburg, PA) | 4:13.45 | Lena Finucane, Whitney Matthew, Asia Walker, Deborah Adjibaba |
| 12 | K | Germantown Friends (Philadelphia, PA) | 4:14.33 | Brooke Heyman, Sarah Bergman, Madeline Hawes, Brooke Pallus |
| 13 | S | Horace Mann (Bronx, NY) | 4:21.54 | Amanda Hill, Annie Lynch, Lavinia Anzai, Renee McDougall |
| 14 | E | Episcopal Academy (Merion Station, PA) | 4:21.84 | Sarah Mumanachit, Catherine Shugrue , Sarah Bernhardt, Laura McDavid |
| 15 | T | Georgetown Visitation (Washington, DC) | 4:25.27 | Katie Schmitz, Katie Pohl, Nada Tramonte, Meghan Smith |
| 16 | M | George School (Newtown, PA) | 4:28.00 | Xavia Bethea, Ama Baffoe-Bonnie, Natalie Ryan, Ayesha Huber |
| 17 | L | Stuart Country Day (Princeton, NJ) | 4:28.96 | Diamond Lewis, Carys Johnson, Chris Volcy, Alex Passano |
| 18 | P | Hun School (Princeton, NJ) | 4:29.69 | Cyndra Couch, Yamira Bell, Jah-Leah Ellis, Meghan Schermgrhorn |
| 19 | V | Abington Friends (Jenkintown, PA) | 4:37.34 | Lillie Ferris, Lindsey Sandmeyer, Samantha Burkey, Dominique Smith |
| 20 | U | Country Day Sacred Heart (Bryn Mawr, PA) | 4:44.26 | Ryanne Baldwin, Caitlyn Scanlon, Molly Marshaleck, Norma Dicocco |
| |
